A procedure for preparing Peptide Derivatives of formula (i), where X is Hydrogen,Alkyl or acyl; A1 is a link or a group composed of 1 to 4 amino acids; A2 is a link or ASP or Glu; A3 is any amino acid; A4 is PHE or N - i - A5 is PHE, Ile, Val, LEU, ala, PHE, Tyr, NLEMet, OR N - i - Val Gly SAR; A6 is or is made; and (ii), where B is a group of Formula - CH2 - RN - CH2 -, - S -, - CH2 -, - ch = CH -, - C or - CH2, CH CH2 (OH) - and - nhcd -Where R is Hydrogen or alkyl or phenyl and the fenilalquileno is replaced or monosustituido alkyl, Hydroxy or alkoxy, halogen; R1 and R2 are isopropyl Isobutyl secbutilo,,,N-butyl and Ethyl 2 - (methylthio), which consists in fixing a attached to a compound ResinFormula (iii) is a butiloxicarbonilo where BOC Protecting Group, and R represents the Circle surrounded by the resin.
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