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Process for the preparation of therapeutically active 7-substituted 3,5-dihydroxyhept-6-amino acids and their derivatives and compounds useful as intermediates

机译:具有治疗活性的7-取代的3,5-二羟基庚基-6-氨基酸及其衍生物和化合物的中间体的制备方法

摘要

7-Substituted 3,5-dihydroxyhept-6-ynoic acids and the derivatives thereof of the formula I IMAGE I as well as the corresponding lactones of the formula II IMAGE II in which R and R DEG have the specified meanings, a process for the preparation of these compounds, the use thereof as pharmaceuticals and pharmaceutical products are described. In addition, new intermediates for the preparation of the compounds of the formula I or formula II are described.
机译:式I I的7-取代的3,5-二羟基庚-6-壬酸及其衍生物以及式II II的相应内酯,其中R和R DEG具有特定含义,描述了这些化合物的制备方法,其作为药物和药物产品的用途。另外,描述了用于制备式I或式II化合物的新中间体。

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