Fremgangsmaate for fremstilling av stikkpiller ved sanmmenpresning, og stikkpiller erholdt ved fremgangsmaaten

摘要

Suppositories which may have a considerably higher content of an active drug than ordinary suppositories, are produced by compressing a suppository mass, which contains a considerable amount of a polyethylene glycol having a molecular weight of at least 4000, preferably 6000. The polyethylene glycol constitutes 20-50 % by weight of the suppository mass, which moreover contains microcrystalline cellulose and/or other additives common in the production of drugs. The obtained suppositories are more convenient to store and use, easier to produce and considerably more concentrated with respect to active substance (up to 75 % by weight) than traditional melt-moulded suppositories.