首页> 外国专利> FURO3,2-bPYRIDINES AND THIENO3,2-bPYRIDINES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS

FURO3,2-bPYRIDINES AND THIENO3,2-bPYRIDINES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS

机译:呋喃[3,2-b]吡啶和噻吩并[3,2-b]吡啶作为白三烯生物合成抑制剂

摘要

Compounds having formula (I) are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis, and allograft rejection and in preventing the formation of atherosclerotic plaques.
机译:具有式(I)的化合物是白三烯生物合成的抑制剂。这些化合物可用作抗哮喘,抗过敏,抗炎和细胞保护剂。它们也可用于治疗心绞痛,脑痉挛,肾小球肾炎,肝炎,内毒素血症,葡萄膜炎和同种异体移植排斥,并预防动脉粥样硬化斑块的形成。

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