EXPRESSION OF HUMAN CMV GLYCOPROTEIN-H USING THE BACULOVIRUS-INSECT CELL EXPRESSION SYSTEM

摘要

Methods for producing recombinant polypeptides which are immunological equivalents of human cytomegalovirus glycoprotein H are disclosed. The methods involve the modification of native CMV gH by C-terminal truncation and subsequent expression in baculovirus/insect cell expression systems. Also disclosed are vectors, recombinant cells and modified recombinant glycoproteins.