EXPRESSION OF HUMAN CMV GLYCOPROTEIN-H USING THE BACULOVIRUS-INSECT CELL EXPRESSION SYSTEM

摘要

A process for producing recombinant polypeptides comprising immunological equivalents of human cytomegalovirus glycoprotein H. The methods consist of the gH Modified CMV by truncation in C-terminus and higher expression in cellular expression systems baculovirus / insect. The invention also relates to vectors, recombinant cells and the recombinant glycoproteins modified.