Monoclonal antibody specific to a fibronectin sequence expressed in transformed cells, hybridoma secreting said antibody and use of said monoclonal antibody in the diagnosis of tumors

摘要

A monoclonal antibody specific to the ED-B sequence of fibronectin expressed in transformed cells. The antibody, which is obtained from a hybridoma deriving from the fusion of immunized mice spleen cells using fibronectin from the culture medium of SV40-transformed embryonic human lung cells with mouse myeloma cells, is useful for the diagnosis of tumors.