Method is used to prepare (+)-Soviet Union -1- phenyl -2- methylamino -1- propyl alcohol

摘要

Pseudoephedrine hydrochloride produces, this is a kind of influence of respiratory mucosa swelling, aminaci D-(- based on intermediate products)-1-phenyl-2-acetone of-1-hydroxyl, when the pH value to hydrogenation crude sodium oxide molybdena reaction mixture is 11 to 12, it is being separated off catalyst, water phase, the pH value of organic phase, concentrated hydrochloric acid 1 to 4 is added, then deletes 80 to 85 % of azeotropicky. The presence of water. Product after the mother liquor generated from suspension, acyluje saponifikuje and merging, izoluje.Pseudoephedrine