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DIAMIDES OF PYRIMIDINE-4,6-DICARBOXYLIC ACID, PROCESS OF THEIR PREPARATION AND MEDICAMENTS BASED THEREON

机译：嘧啶-4,6-二羧酸的二酰胺，其制备方法和基于其的药物

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摘要

The invention relates to pyrimidine-4,6-dicarboxamides of the formula I …IMAGE… in which R1 and R2 have the stated meanings. The compounds according to the invention inhibit proline hydroxylase and lysine hydroxylase and can be used as fibrosuppressants and immunosuppressants.

机译：本发明涉及式I…IMAGE>的嘧啶-4，6-二甲酰胺，其中R 1和R 2具有所述含义。根据本发明的化合物抑制脯氨酸羟化酶和赖氨酸羟化酶，并且可以用作纤维抑制剂和免疫抑制剂。

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公开/公告号CZ458390A3

专利类型
公开/公告日1995-01-18

原文格式PDF
申请/专利权人 HOECHST AKTIENGESELLSCHAFT;
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申请/专利号CS19900004583
发明设计人 BAADER EKKEHARD DR.;BICKEL MARTIN DR.;GUNZLER-PUKALL VOLKMAR DR.;HENKE STEPHAN DR.;
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申请日1990-09-20
分类号C07D239/28;A61K31/505;
国家 CZ
入库时间 2022-08-22 04:20:08

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