首页> 外国专利> OPTICALLY ACTIVE THIAZOLOISOINDOLINONE DERIVATIVES WITH ANTIVIRAL EFFECT.

OPTICALLY ACTIVE THIAZOLOISOINDOLINONE DERIVATIVES WITH ANTIVIRAL EFFECT.

机译:具有抗病毒作用的光学活性噻唑并异吲哚啉酮衍生物。

摘要

The present invention relates to optically active thiazoloisoindolinones of general formulae (I) and (II) where: R is a hydrogen atom or a straight-chained or branched, saturated or unsaturated aliphatic radical with 1-7 carbon atoms which may also be substituted by phenyl, or a phenyl ring which may be singly or multiply substituted by C1-C4-alkyl, C1-C4-alkoxy, hydroxy, trifluoromethyl, C1-C4-alkyl sulphonyl or a halogen; n is 0, 1 or 2; and their pharmacologically acceptable salts and tautomers. The object of the invention also includes medicaments containing the compounds of formula (I) or (II) and their use for the production of medicaments to treat viral or retroviral infections.
机译:本发明涉及通式(I)和(II)的光学活性噻唑并异吲哚啉酮,其中:R是氢原子或具有1-7个碳原子的直链或支链,饱和或不饱和脂族基团,它们也可以被取代。苯基,或可以被C 1 -C 4烷基,C 1 -C 4烷氧基,羟基,三氟甲基,C 1 -C 4烷基磺酰基或卤素单或多取代的苯环; n为0、1或2;及其药学上可接受的盐和互变异构体。本发明的目的还包括含有式(I)或(II)的化合物的药物及其在制备用于治疗病毒或逆转录病毒感染的药物中的用途。

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