首页> 外国专利> A phosphatidylethanolamine binding protein derived from a human glioblastoma cell line and DNA encoding it

A phosphatidylethanolamine binding protein derived from a human glioblastoma cell line and DNA encoding it

机译:源自人胶质母细胞瘤细胞系的磷脂酰乙醇胺结合蛋白和编码该蛋白的DNA

摘要

The present invention is related to novel polypeptide consisting of 187 amino acids which is produced in a human glioblastoma cell line, a method of producing it, DNA encoding the said polypeptide, a fragment capable of selectively hybridizing to the DNA sequence, a replication or expression vector comprising the DNA and a host cell transformed with the replication or expression vector. The polypeptide of the present invention may be useful for the prevention of or in the treatment of aplasia or abnormal proliferation, of cells, depression or enhancement of activity, tumors, or the deseases induced by lipid metabolism abnormality.
机译:本发明涉及在人胶质母细胞瘤细胞系中产生的由187个氨基酸组成的新型多肽,其生产方法,编码所述多肽的DNA,能够选择性地与DNA序列杂交,复制或表达的片段。载体,其包含DNA和用复制或表达载体转化的宿主细胞。本发明的多肽可用于预防或治疗细胞发育不全或异常增生,降低或增强活性,肿瘤或脂质代谢异常引起的疾病。

著录项

  • 公开/公告号EP0628631A1

    专利类型

  • 公开/公告日1994-12-14

    原文格式PDF

  • 申请/专利权人 ONO PHARMACEUTICAL CO. LTD.;

    申请/专利号EP19940108321

  • 发明设计人 NAITO TAKAYUKI;NAKADE SHINJI;

    申请日1994-05-30

  • 分类号C12N15/12;C12P21/08;C12N1/21;A61K37/02;C07K13/00;C12P21/02;

  • 国家 EP

  • 入库时间 2022-08-22 04:14:11

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