A novel peptide and a platelet aggregation inhibitor using the same, a blood coagulation inhibitor for extracorporeal circulation, a cell adhesion inhibitor, a cancer metastasis inhibitor, a platelet protective agent for blood transfusion,

摘要

A novel peptide derivative having a platelet aggregation inhibiting action, a blood coagulation inhibiting action and a cell adhesion inhibiting action having RGD as a basic skeleton.;In view of the above-mentioned effects of the peptide derivatives, it is also possible to use the platelets which are effective against platelet thrombosis and thrombotic occlusion after treatment in the treatment of thrombus collapse, which include the peptide derivative as an active ingredient, An aggregation inhibitor; A cell adhesion inhibitor, a cancer metastasis inhibitor, and a platelet drug prophylactic agent for blood transfusion, which can inhibit blood clotting, which is the main cause of thrombus formation during circulation in the circulation, for cardiopulmonary bypass.;The present invention also provides a platelet pack for blood transfusion comprising the peptide derivative in a pack for platelet transfusion.