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And methods of treatment for improvement of diagnostic reagents and stiff-man syndrome and diabetes
And methods of treatment for improvement of diagnostic reagents and stiff-man syndrome and diabetes
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机译:用于改善诊断试剂和僵硬综合症和糖尿病的治疗方法
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摘要
The invention provides fragments of GAD65 that are specifically reactive with at least one class of GAD65 autoantibody. Most fragments are substantially free of N-terminal amino acids that would otherwise limit solubility. Different fragment contain epitopes for different classes of GAD65 autoantibodies. The fragments are used in methods of diagnosing and treating insulin dependent diabetes mellitus and stiff man syndrome.
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