The present invention provides a nucleic acid having a nucleotide sequence coding for Sor h I, a major allergen of Sorghum halepense, and fragments thereof. The present invention also provides purified Sor h I or at least one fragment thereof, produced in a host cell transformed with a nucleic acid sequence coding for Sor h I, or at least one fragment thereof and fragments of Sor h prepared synthetically. Sor h I and fragments thereof are useful for diagnosing, treating, and preventing allergy to Johnson grass pollen.
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机译:本发明提供了具有编码Sor h I的核苷酸序列的核酸,所述高粱是哈尔滨高粱的主要变应原,及其片段。本发明还提供了纯化的Sor h I或其至少一个片段,其在用编码Sor h I的核酸序列或其转化的至少一个片段和Sor h的片段合成的宿主细胞中产生。 Sor h I及其片段可用于诊断,治疗和预防对约翰逊草花粉的过敏。
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