Vaccine against avian infectious bronchitis virus, the use of an inactivated avian infectious bronchitis virus for the preparation thereof as well as vaccinesæt

摘要

The present invention provides vaccines containing inactivated avian infectious bronchitis virus VLO 10110/AVI/9 and/or an inactivated virus strain serologically related thereto the immune response to which in birds is enhanced by "priming" with a live heterologous strain of avian infectious bronchitis virus. Immunisation of poultry against infectious bronchitis using such a vaccine does not require initial vaccination or "priming" of the poultry with a live vaccine of the same strain, thus enabling "priming" to be effected using a well-tried conventional live heterologous vaccine, for example a live vaccine to an avian infectious bronchitis virus of the Massachusetts serotype.