Attenuated Avian Infectious Bronchitis Virus and Vaccine for Avian Infectious Bronchitis Comprising the Same

摘要

PURPOSE: An attenuated avian infectious bronchitis virus and a vaccine containing the same for avian infectious bronchitis are provided to prevent avian infectious bronchitis virus. CONSTITUTION: An attenuated avian infectious bronchitis virus strain is made by attenuating toxicity to chicken by sub-culturing virus stain and S1 protein is mutated. The mutant S1 protein is mutated from serine to tyrosine. The mutant S1 protein has an amino acid sequence of sequence number 4. The attenuated avian infectious bronchitis virus strain is IBV AVR1/08 strain(deposit number: KCTC 11467BP). A vaccine for preventing avian infectious bronchitis for preventing respiratory avian infectious bronchitis contains the attenuated avian infectious bronchitis virus strain. The vaccine additionally contains an adjuvant.