首页>
外国专利>
Isolated, MAGE-3-derived peptides, which form complexes with HLA-A2 molecules, and their uses
Isolated, MAGE-3-derived peptides, which form complexes with HLA-A2 molecules, and their uses
展开▼
机译:与HLA-A2分子形成复合物的分离的MAGE-3衍生肽及其用途
展开▼
页面导航
摘要
著录项
相似文献
摘要
Tumor rejection antigens derived from tumor rejection precursor MAGE-3 have been identified. These "TRAS" bind to the MHC-class I molecule HLA-A2, and the resulting complexes stimulate the production of cytolytic T cell clones which lyse the presenting cells. The peptides and complexes may be used diagnostically, therapeutically, and as immunogens for the production of antibodies, or as targets for the generation of cytolytic T cell clones.
展开▼