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And how to use them isolated MAGE-3-derived peptide complex with HLA-A2 molecule
And how to use them isolated MAGE-3-derived peptide complex with HLA-A2 molecule
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机译:以及如何使用它们分离具有HLA-A2分子的MAGE-3衍生肽复合物
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摘要
Tumor rejection antigens derived from tumor rejection precursor MAGE-3 have been identified. These "TRAS" bind to the MHC-class I molecule HLA-A2, and the resulting complexes stimulate the production of cytolytic T cell clones which lyse the presenting cells. The peptides and complexes may be used diagnostically, therapeutically, and as immunogens for the production of antibodies, or as targets for the generation of cytolytic T cell clones.
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