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Antibiotic a 40926 ester derivatives process for their preparation and their use as medicaments

机译:抗生素40926酯衍生物的制备方法及其用作药物的用途

摘要

The present invention relates to novel ester derivatives of antibiotic A 40926 complex and its N-acylaminoglucuronyl aglycone. The compounds of the invention are prepared according to an esterification process involving reaction of an A 40926 substrate with an excess of the selected alkanol in the presence of concentrated mineral acid and are active as antibiotics.
机译:本发明涉及抗生素A 40926复合物的新型酯衍生物及其N-酰基氨基葡糖醛酸酰基糖苷配基。本发明的化合物是根据酯化方法制备的,该方法包括在浓的无机酸存在下,A 40926底物与过量的所选链烷醇反应,并具有抗菌活性。

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