首页> 外国专利> Joderte bor-forbindelser som er anvendelige som röntgenkontrastmidler, og farmasöytiske preparater inneholder disse

Joderte bor-forbindelser som er anvendelige som röntgenkontrastmidler, og farmasöytiske preparater inneholder disse

机译:可用作X射线造影剂的碘化硼化合物和药物制剂均含有这些

摘要

The invention relates to new organic boron compounds having a monomer structure (I): [BxCyH¿(x+y-t-w)?ItZw], 2/rQ and a dimer structure (II): {[B12H¿(12-t-w)?ItZw]-N(R)-[B12H¿(12-t-w)?ItZw]}, 4/rQ, characterized in that they contain a high molar percentage of iodine, and are useful as radio-opaque agents in uroangiography, cardioangiography, etc., as well as for selectively visualizing organs or body systems such as the liver, the spleen or the lymphatic system. The compounds having the general formulas (I) and (II) are also useful in the selective therapy of tumors. The invention also relates to pharmaceutical preparations which contain the claimed compounds having the general formulas (I) and (II).
机译:本发明涉及具有单体结构(I):[BxCyH-(x + ytw)≤ItZw],2 / rQ和二聚物结构(II)的新的有机硼化合物:{[B 12 H-(12-tw)≤ItZw ] -N(R)-[B12H¿(12-tw)?ItZw]},4 / rQ,其特征在于它们含有高摩尔百分比的碘,并在尿道造影,心血管造影等中用作不透射线的药物以及选择性地观察器官或身体系统,例如肝脏,脾脏或淋巴系统。具有通式(I)和(II)的化合物也可用于肿瘤的选择性治疗。本发明还涉及含有所要求保护的具有通式(I)和(II)的化合物的药物制剂。

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