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ANTIFUNGAL-COATED BEADS: BEAD CORE, FUNGICIDE AND POLYMER COATING, AND A POLYMER SEALING COAT; PHARMACEUTICAL DOSAGE
ANTIFUNGAL-COATED BEADS: BEAD CORE, FUNGICIDE AND POLYMER COATING, AND A POLYMER SEALING COAT; PHARMACEUTICAL DOSAGE
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机译:抗真菌涂层的珠:珠芯,杀菌剂和聚合物涂层以及聚合物密封涂层;药物剂量
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PCT No. PCT/EP93/02327 Sec. 371 Date Mar. 13, 1995 Sec. 102(e) Date Mar. 13, 1995 PCT Filed Aug. 27, 1993 PCT Pub. No. WO94/05263 PCT Pub. Date Mar. 17, 1994The present invention is concerned with beads comprising a 25-30 mesh core, a coating of a hydrophilic polymer and an antifungal agent, and a seal outer coating layer; pharmaceutical dosage forms comprising said beads and a method of preparing said beads. Preferred antifungal agents are lipophilic azole antifungals, such as itraconazole and saperconazole.
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