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Polymer coated superparamagnetic beads walking on polymer coated surface

机译:聚合物涂覆的超顺磁珠在聚合物涂覆的表面上行走

摘要

Biology has provided us with many organisms that are able to propel themselves through a fluid using cilia or flagella. This provides inspiration to create controllable systems that cannot only propel an organism or device through a fluid but can also create a fluid flow. Research has focused on how to mimic the mechanisms of these organisms for the use in microfluidic devices or drug delivery. This work examines walkers that are created using superparamagnetic beads placed in a rotating external magnetic field. Dipoles align in the beads so they assemble into rotors. These rotors follow the rotating magnetic field and are able to translate across a surface. This work looks at the effect of coating the beads and the surface with a polymer, Polyethylene Glycol(PEG). PEG has been shown to undergo a transition from an expanded state to a collapsed state under certain salt concentrations and temperature ranges. By looking at this transition we can see if the use of a polymer could affect the velocity of the rotors and if PEG could be used to control the velocity of the rotors or to initiate a transition. This transition is only seen by recording the velocity of the rotors, future research using other experimental procedures might be helpful in finalizing the transition of PEG in NaCl. It was unclear from these experiments whether the velocity of the rotors is dependent on the state of the polymer.
机译:生物学为我们提供了许多生物,它们能够利用纤毛或鞭毛推动自身通过液体。这为创建可控系统提供了灵感,该系统不仅可以推动生物体或设备通过流体,而且还可以创建流体流。研究集中在如何模仿这些生物体在微流体装置或药物输送中的使用机理。这项工作研究了使用放置在旋转外部磁场中的超顺磁性珠子制成的助行器。偶极在磁珠中对齐,因此它们组装成转子。这些转子跟随旋转的磁场并能够在整个表面上平移。这项工作着眼于用聚合物聚乙二醇(PEG)覆盖珠子和表面的效果。已经证明在某些盐浓度和温度范围内,PEG经历从膨胀状态到塌陷状态的转变。通过查看此过渡,我们可以看到使用聚合物是否会影响转子的速度,以及是否可以将PEG用于控制转子的速度或启动过渡。仅通过记录转子的速度才能看到这种转变,将来使用其他实验程序进行的研究可能有助于最终确定NaCl中PEG的转变。从这些实验中还不清楚转子的速度是否取决于聚合物的状态。

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