首页> 外国专利> New hydrazino and hydroxyamino-14beta-hydroxyandrostane derivatives active on the cardio-vascular system, processes for their preparation and pharmaceutical compositions containing same

New hydrazino and hydroxyamino-14beta-hydroxyandrostane derivatives active on the cardio-vascular system, processes for their preparation and pharmaceutical compositions containing same

机译:对心血管系统有活性的新肼基和羟氨基-14β-羟基雄烷衍生物,其制备方法和含有它们的药物组合物

摘要

Hydrazino and hydroxyamino- 14β-hydroxyandrostane derivatives having general formula (I): wherein the symbol means α or β configuration and A, B, R¹, R², R³ and R⁴ have the manings given in the description;a process for producing same and their use for the preparation of a medicament for the treatment of cardiovascular disorder such as heart failure and hypertension are disclosed.
机译:具有通式(I)的肼基丁醇和羟基氨基-14β-羟基雄烷酮衍生物: <图像文件=“ IMGA0001.GIF” he =“ 78” imgContent =“ chem” imgFormat =“ GIF” wi =“ 76” /> 其中符号表示α或β配置,A,B,R¹ ,R 2,R 3和R 3具有描述中给出的名称;公开了其生产方法及其在制备用于治疗心血管疾病例如心力衰竭和高血压的药物中的用途。

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