Monoclonal antibodies against c-kit and method of detecting a malignancy using c-kit specific antibodies

摘要

The invention concerns monoclonal antibodies against the human c-kit receptor which are obtainable from the cell lines DSM ACC 2007, DSM ACC 2008 and DSM ACC 2009 or are capable of binding to the c-kit receptor in an equivalent manner to the antibodies produced by the cell lines DSM ACC 2007, DSM ACC 2008 or DSM ACC 2009. The present invention also concerns a method for testing the malignancy of tumours of haematopoietic cells, of seminomas or small-celled lung carcinoma in which a tissue sample is incubated with at least one monoclonal antibody against the c- kit receptor according to the present invention and subsequently bound antibodies are detected by means of known methods.