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Tumor cell invasion-inhibiting peptides, peptide complexes and cancer metastasis inhibitors

机译:抑制肿瘤细胞侵袭的肽,肽复合物和癌症转移抑制剂

摘要

The present invention is a peptide having from 5 to 20 amino acid residues having tumor cell invasion-inhibiting activities. As such a peptide, a peptide represented by any one of the formulas (1) to (13) is preferred among peptides.PPFurther, the present invention is a cancer metastasis inhibitor comprising the above peptide as an active ingredient.PPFurthermore, the present invention is a peptide complex having a peptide having tumor cell invasion-inhibiting activities and a polymer derived from a vital body chemically bonded to each other. As such a peptide, a peptide represented by any one of the formulas (1) to (14) is preferred among peptides. As the polymer derived from a vital body, a protein such as albumin or globulin is preferred. PPStill further, the present invention is a cancer metastasis inhibitor comprising the above peptide complex as an active ingredient.
机译:本发明是具有5至20个氨基酸残基的具有肿瘤细胞侵袭抑制活性的肽。作为这样的肽,在肽中优选由式(1)至(13)中的任一个表示的肽。此外,本发明是一种癌症转移抑制剂,其包含上述肽作为活性成分。此外,本发明是一种肽复合物,其具有具有抑制肿瘤细胞侵袭活性的肽和衍生自彼此化学结合的生命体的聚合物。作为这样的肽,在肽中优选由式(1)至(14)中的任一个表示的肽。作为源自生命体的聚合物,优选蛋白质例如白蛋白或球蛋白。此外,本发明是一种癌转移抑制剂,其包含上述肽复合物作为活性成分。

著录项

  • 公开/公告号US5548062A

    专利类型

  • 公开/公告日1996-08-20

    原文格式PDF

  • 申请/专利权人 ASAHI GLASS COMPANY LTD.;

    申请/专利号US19930157437

  • 发明设计人 HIROMICHI KUMAGAI;ATSUSHI ISOAI;YUKO HAMA;

    申请日1993-11-26

  • 分类号A61K38/00;A61K38/04;C07K5/00;C07K7/00;

  • 国家 US

  • 入库时间 2022-08-22 03:38:02

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