首页> 外国专利> N-(1,(1-1)-dialkyloxy)-and N-(1,(1-1)-dialkenyloxy alk-1-yl-N-N,N- tetrasubstituted ammonium lipids and uses therefor

N-(1,(1-1)-dialkyloxy)-and N-(1,(1-1)-dialkenyloxy alk-1-yl-N-N,N- tetrasubstituted ammonium lipids and uses therefor

机译:N-(1,(1-1)-二烷氧基)-和N-(1,(1-1)-二烯氧基氧基烷基-1-基-N-N,N-四取代的铵脂质及其用途

摘要

This invention relates to compounds of the formula ##STR1## or an optical isomer thereof wherein R.sup.1 and R.sup.2 are the same or different and are an alkyl or alkenyl group of 6 to 24 carbon atoms; R. sup.3, R.sup.4 and R.sup.5 are the same or different and are alkyl of 1 to 8 carbon atoms, aryl, aralkyl of 7 to 11 carbon atoms, or when two or three of R.sup.3, R.sup.4, and R.sup.5 are taken together to form quinuclidino, piperidino, pyrrolidino, or morpholino; n is 1 to 8; and X is a pharmaceutically acceptable anion.
机译:本发明涉及式## STR1 ##的化合物或其光学异构体,其中R 1和R 2相同或不同,且为6至24个碳原子的烷基或烯基。 R.sup.3,R.sup.4和R.sup.5相同或不同,且为1至8个碳原子的烷基,芳基,7至11个碳原子的芳烷基,或当R中的两个或三个。 sup.3,R.4和R.5一起形成奎尼利丁,哌啶子基,吡咯烷基或吗啉代; n为1至8; X是药学上可接受的阴离子。

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