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Monoclonal antibody specific for antigens in mouse inbred strains

机译:对小鼠近交系抗原具有特异性的单克隆抗体

摘要

A novel monoclonal antibody of IgG1/ subclass, characterized in that it recognizes antigens specifically present in mouse inbred strains consisting of DBA/1, CE/J, SM/J, IQI, PL/J, SWM/Ms, RIIIS/J, RFM/MsNrs and C3H and its congenic mouse strains thereof, wherein one of said antigens has a molecular weight of 66,000 and the other has a molecular weight of 68,000 and said antigens are present in the mitochondria of C3H mouse strain.PPThe present invention also provides a hybridoma cell line which produces the above monoclonal antibody, a method for identifying the origin of a cell derived from a mouse, and a reagent for identifying the origin of a cell derived from a mouse.
机译:一种新型的IgG1 /亚类单克隆抗体,其特征在于它可以识别由DBA / 1,CE / J,SM / J,IQI,PL / J,SWM / Ms,RIIIS / J,RFM组成的小鼠近交系中特异存在的抗原/ MsNrs和C3H及其同系小鼠品系,其中一种抗原的分子量为66,000,另一种抗原的分子量为68,000,并且所述抗原存在于C3H小鼠品系的线粒体中。本发明还提供产生上述单克隆抗体的杂交瘤细胞系,鉴定源自小鼠的细胞的来源的方法,以及鉴定源自小鼠的细胞的来源的试剂。

著录项

  • 公开/公告号US5552287A

    专利类型

  • 公开/公告日1996-09-03

    原文格式PDF

  • 申请/专利权人 RIKAGAKU KENKYUSHO;

    申请/专利号US19940261301

  • 发明设计人 MORIAKI KUSAKABE;TERUYO SAKAKURA;

    申请日1994-06-16

  • 分类号G01N33/573;

  • 国家 US

  • 入库时间 2022-08-22 03:37:57

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