首页> 外国专利> Pharmaceutical composition use of an amount of (i) a standardized antigen together with an amount of (ii) a polypeptide and product containing an amount of (i) a standardized antigen together with an amount of (ii) a polypeptide

Pharmaceutical composition use of an amount of (i) a standardized antigen together with an amount of (ii) a polypeptide and product containing an amount of (i) a standardized antigen together with an amount of (ii) a polypeptide

机译:药物组合物的用途:一定量的(i)标准化抗原与一定量的(ii)多肽以及含有一定量的(i)标准化抗原与一定量的(ii)多肽的产品

摘要

The invention is directed to methods for treating autoimmune diseases such as multiple sclerosis by orally administering a bystander antigen such as myelin basic protein or proteolipid protein in conjunction with a polypeptide having Type I interferon activity in such a manner as to induce oral tolerance to the bystander antigen resulting in suppression of the autoimmune response.
机译:本发明涉及用于治疗自身免疫性疾病如多发性硬化症的方法,该方法通过口服给予旁观者抗原如髓磷脂碱性蛋白或蛋白脂蛋白与具有I型干扰素活性的多肽一起以诱导对旁观者口服耐受的方式抗原导致自身免疫反应的抑制。

著录项

  • 公开/公告号BR9507451A

    专利类型

  • 公开/公告日1997-08-05

    原文格式PDF

  • 申请/专利权人 BRIGHAM AND WOMENS HOSPITAL;

    申请/专利号BR19959507451

  • 发明设计人 DAVID A HAFLER;HOWARD L WEINER;

    申请日1995-04-07

  • 分类号A61K38/17;A61K38/21;A61K38/28;A61K38/39;

  • 国家 BR

  • 入库时间 2022-08-22 03:27:40

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