首页> 外国专利> Pharmaceutical composition use of a non-interferon polypeptide use of a quantity of a standardized antigen and a quantity of a non-interferon polypeptide and product containing (1) a quantity of a standardized antigen and (11) a quantity of a non-interferon polypeptide

Pharmaceutical composition use of a non-interferon polypeptide use of a quantity of a standardized antigen and a quantity of a non-interferon polypeptide and product containing (1) a quantity of a standardized antigen and (11) a quantity of a non-interferon polypeptide

机译:非干扰素多肽的药物组合物用途一定数量的标准化抗原和一定数量的非干扰素多肽的使用以及含有(1)一定数量的标准化抗原和(11)一定数量的非干扰素多肽的产品

摘要

The invention is directed to methods for treating autoimmune diseases such as multiple sclerosis by orally administering a bystander antigen such as myelin basic protein or proteolipid protein in conjunction with a non-interferon polypeptide having Th2-enhancing cytokine activity in such a manner as to induce oral tolerance to the bystander antigen resulting in suppression of the autoimmune response.
机译:本发明涉及用于治疗自身免疫疾病如多发性硬化症的方法,该方法通过口服给予旁观者抗原如髓磷脂碱性蛋白或蛋白脂蛋白与具有增强Th2的细胞因子活性的非干扰素多肽一起以诱导口服的方式进行对旁观者抗原的耐受性导致自身免疫反应的抑制。

著录项

  • 公开/公告号BR9507452A

    专利类型

  • 公开/公告日1997-08-05

    原文格式PDF

  • 申请/专利权人 BRIGHAM AND WOMENS HOSPITAL;

    申请/专利号BR19959507452

  • 发明设计人 HOWARD L WEINER;YOUHAI CHEN;

    申请日1995-04-07

  • 分类号A61K38/17;A61K38/19;A61K38/20;A61K38/26;A61K38/28;A61K38/39;

  • 国家 BR

  • 入库时间 2022-08-22 03:27:40

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