Method for Preparation of Enantiomers of demetiltramadol or -

摘要

1.0-demethyltramado gnomes preparation process, characterized by: a pure gold salt from tramadol as its base; diante acido L - (+) - cake precipitated in the enan tiomer (-) of tramadol; The base is released and becomes (-) of 0-de-methyltramardo by hydrogenation of diisobutyl aluki micro water; in the mother water of the precipitate, prepare the corresponding sign (+) of 0-demethyltramardo, leaving the base of tramador to react with hydrogenation diisobutyl aluminum. 0-demethytramitrado application prepared according to conditions 1 to 6It is characterized by a racemato or an e-nanteromer as the form of foundation and / or salt, a racemato or a dwarf as the form of foundation and / or salt alone or in combination, and an application as a medium for analysis.