RESERVOIR IMPREGNABLE WITH AN ACTIVE SOLUTION FOR AN IONTOPHORETIC TRANSDERMIC DRUG DELIVERY DEVICE AND METHOD OF MANUFACTURE OF SUCH A RESERVOIR

摘要

PCT No. PCT/FR94/00974 Sec. 371 Date Feb. 26, 1996 Sec. 102(e) Date Feb. 26, 1996 PCT Filed Aug. 3, 1994 PCT Pub. No. WO95/06496 PCT Pub. Date Mar. 9, 1995The reservoir loaded with a divided material which can be impregnated with the solution of active principle, comprises a) a support sheet (1) made of a cavitied material which is permeable to the solution and capable of contributing to the mechanical strength of the reservoir b) a layer (3) of particles of the impregnatable material and c) a substrative layer (2) interposed between one face of the support sheet (1) and the layer of particles (3) in order to hold the latter on the support sheet (1), this substrative layer (2) consisting of a substance which is miscible with the solution of active principle.