Methods and compositions for the use of env polypeptides and anti-HIV env antibodies.

摘要

COVER PROTEIN human immunodeficiency virus, or fragments thereof, that are capable of binding cell receptor BOOSTER T4 are useful in therapeutically effective doses for the treatment of immuno-inflammatory disorders or diseases. Amino acid residues WHICH ARE ESSENTIAL PART OF DOMAIN T4 receptor binding HIV sheath fall within a sequence of 64 REMAINS, extending from 411 to 454 REMAINS OF ISOLATED 3B. THIS DOMAIN IS useful as a vaccine component, or WHITE AS Cytotoxic T cells when conjugated to a linker WHITE CELL substance. BOOT HIV, which is free of a domain linker RECEPTOR FUNCTIONAL T4 is useful as a vaccine to immunize against HIV infection. Also they provided CAPABLE OF LINKING THIS DOMAIN ANTIBODY FOR USE AND DIAGNOSTIC THERAPEUTIC. It DESCRIBED an immunotoxin comprising a monoclonal FOR CELL SURFACE ANTIGEN virally encoded. Also it disclosed a method for removing cells affected virally cells, such as HIV INFECTED, comprising administering AN INFECTED CELLS A therapeutically effective amount of the immunotoxin.