A medicament delivery device (10) has a reservoir within a housing (11) andmeans for driving medicament from the reservoir. The device is provided with afilling mechanism upon which a medicament container (19) sealed by apenetrable stopper (25) is mounted. The mechanism comprises an internal bore(20) which accommodates an internal rod (21) from which a needle (22)projects. Needle (22) is hollow and is in communication with the reservoir. Inorder to fill the reservoir, the container (19) is pressed into the bore (20),causing the needle (22) to pierce the stopper (25), the stopper abuttingagainst the rod (21) and acting as a piston to drive medicament from thecontainer (19) as the container (19) is pushed into the bore (20) and movesrelative to the stopper (25). Thus, the reservoir can be filled with thesterile medicament which is stable when stored in the container (19), and thefilling is easily accomplished without the use of a syringe. A furtheradvantageous feature is provided by a delivery needle which is mounted on theperiphery of the lower surface of the housing. This configuration allows thedriving means to be located adjacent to the skin, thereby, providing a morestable temperature and more predictable operation of the device.
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