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Method of identifying the molecules and molecules that home to a selected organ or tissue in vivo

机译:在体内鉴定归巢于选定器官或组织的分子和分子的方法

摘要

The present invention provides an in vivo method for identifying molecules that home to a selected organ or tissue. In addition, the invention provides peptides that home to a selected organ or tissue. For example, the invention provides peptides that selectively home to an organ such as brain or kidney or to a tissue such as a tumor tissue. The invention further provides methods of using an organ homing molecule, for example, to target an agent such as a drug to a selected organ or to identify the target molecule expressed by the selected organ.
机译:本发明提供了用于鉴定归巢于所选器官或组织的分子的体内方法。另外,本发明提供了归巢于选定器官或组织的肽。例如,本发明提供了选择性地归巢于诸如大脑或肾脏之类的器官或归于诸如肿瘤组织之类的组织的肽。本发明进一步提供了使用器官归巢分子,例如将诸如药物的试剂靶向选定器官或鉴定选定器官表达的靶分子的方法。

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