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MEDICAL COMPOSITION FOR TREATING PATIENT ACCOMPANIED BY BRONCHOCONSTRICTION AND APPARATUS FOR INHALATION OF THE SAME

机译:治疗支气管扩张性伴随患者的药物组合物和用于吸入该药物的装置

摘要

PROBLEM TO BE SOLVED: To obtain a medical composition capable of relaxing bronchoconstriction, especially constriction of bronchial smooth muscle by constituting the composition of a mixed gas containing NO gas and O2 gas obtained by mixing a specific component therewith just before inhalation by a patient. SOLUTION: This medical composition comprising NO gas and a mixed gas containing O2 is obtained by mixing, for example, a gas containing compressed NO gas in N2 gas with O2 /N2 mixed gas just before inhalation to a patient. The composition is inhaled by mammals having pulmonary vascularity contraction, asthma, etc., under one or more conditions corresponding to (a) a state of including no smoke of tobacco, (b) a state of inhaling as a mixed gas of NO gas, O2 gas and N2 gas, (c) a state of the inhaling concentration of NO gas being 1ppm, preferably 80-180ppm, (d) a state of maintaining the concentration of NO2 concentration under the safety limit (=1ppm) or (e) a state of inhaling for =3min, preferably =6min.
机译:要解决的问题:通过构成包含NO气体和O 2气体的混合气体的组合物来获得能够缓解支气管狭窄,特别是支气管平滑肌收缩的医疗组合物,所述混合气体是在患者吸入之前通过将特定成分与其混合而获得的。解决方案:这种包含NO气体和含O2混合气体的医疗组合物是通过在吸入患者之前,例如将N2气体中包含压缩NO的气体与O2 / N2混合气体混合而获得的。在具有以下条件的一种或多种条件下,该组合物被具有肺血管收缩,哮喘等症状的哺乳动物吸入:(a)禁止吸烟的状态,(b)作为NO气体的混合气体的吸入状态, O2气体和N2气体,(c)NO气体的吸入浓度为1ppm,优选80-180ppm的状态,(d)将NO2浓度保持在安全极限(<= 1ppm)或(e )吸入> = 3分钟,优选> = 6min的状态。

著录项

  • 公开/公告号JPH10158175A

    专利类型

  • 公开/公告日1998-06-16

    原文格式PDF

  • 申请/专利权人 GENERAL HOSPITAL CORP:THE;

    申请/专利号JP19970036785

  • 发明设计人 ZAPOL WARREN M;FROSTELL CLAES;

    申请日1991-12-05

  • 分类号A61K33/00;A61M16/10;

  • 国家 JP

  • 入库时间 2022-08-22 03:07:40

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