Clinical and functional responses to salbutamol inhaled via different devices in asthmatic patients with induced bronchoconstriction

摘要

AimsThis study aimed at evaluating changes in airway patency, lung volumes and perception of breathing discomfort intensity following salbutamol administration via the Diskus dry-powder inhaler (DPI) or a pressurized metered-dose inhaler with the Volumatic valved holding chamber (pMDI +Volumatic) in asthmatic patients with methacholine-induced bronchoconstriction.