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New DNA, novel polypeptides and novel antibodies

机译:新DNA,新多肽和新抗体

摘要

The present invention is compared to the mRNA expressed in normal human brains and is selected from DNA having a nucleotide sequence of sequence 1 to 17 which is complementary to the RNA chain of the mRNA that is changing its expression in the brain of patients with Alzheimer's disease and DNA thereof A DNA fragment in which one or more bases are missing, but substituted with other bases or DNA or DNA is added to one or more bases, and DNA hybridized with the DNA, a polypeptide encoded by the DNA, the polypeptide The present invention relates to an antibody to recognize a peptide and the DNA, the polypeptide, and the diagnosis, treatment and research of an Alzheimer's disease patient using the antibody.
机译:将本发明与正常人脑中表达的mRNA进行比较,并选自具有1至17个核苷酸序列的DNA,该核苷酸序列与改变阿尔茨海默氏病患者脑中表达的mRNA的RNA链互补及其DNA及其DNA片段,其中缺失一个或多个碱基但被其他碱基取代或被DNA或DNA取代的DNA片段添加至一个或多个碱基,并与该DNA杂交,该DNA编码的多肽,该多肽。本发明涉及识别肽和DNA,多肽的抗体,以及使用该抗体的阿尔茨海默氏病患者的诊断,治疗和研究。

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