The preparation method of derivative is used for the fractionation enantiomer of chromatography by how sugar-substituted aromatic series with them as carrier

摘要

The present invention relates to the method for preparing polysaccharide-N- aryl-carbamates,The compound exists in the form of being suitable for use as chromatographic support,The method includes to aryl primitive may in substituted polysaccharide carbamate,With vigorous stirring,The solution containing N- aryl -1- lower alkyl-amino formic acid esters of organic solvent is added,Until polysaccharide derivates are completely dissolved,Then the aqueous solution containing high molecular weight surface activating agent is added and continues to stir,Organic solvent is removed from obtained emulsion,Separation solid particle is simultaneously cleaned and is dried. Obtained polysaccharide derivates can be used as the support material of enantiomer chromatography.