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Cis-epoxide derivatives useful as irreversible HIV protease inhibitors and process and intermediates for their preparation.

机译:顺式环氧衍生物可用作不可逆的HIV蛋白酶抑制剂及其制备方法和中间体。

摘要

The present invention provides cis-epoxide compounds represented by formula (I-1), (I-2) or (I-3) which are useful for treating or preventing diseases caused by HIV infection: CHEM wherein: A, B, D, E, R1, R10, R11, K, G, Q, r and J have the meanings as defined in the specification. IMAGE
机译:本发明提供了由式(I-1),(I-2)或(I-3)表示的顺式环氧化合物,其可用于治疗或预防由HIV感染引起的疾病:其中:A,B, D,E,R 1,R 1> 0,R 1> 1,K,G,Q,r和J具有说明书中定义的含义。 <图像>

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