2、 The preparation technology of tin-2 - (2-amino-4-il) - 2-acetylmethoxymethyl ether was studied.

摘要

2-2 - (2-amino-4-il) - 2-acetomethoxyacetyl (essentially no anti isomer) syn chlorohydrides, The hydrochloric acid of acetic anhydride is reacted with a mixture containing at least one chloridized oxalilo molal equivalent and at least one molar equivalent so that the content of diethylmethylamine in this chloridized oxalilo in N.N. is slightly higher than that in N.NInert organic solvents below - 10 ℃: this process includes, inter Alia, that the content of oxalilo chloride is equivalent to 1.0 to 2.0 times of the abrasive, while the content of dimethylamine is slightly chemical excess compared with oxalilo chloride.Or alternatively, the content of dimethylamine chloride is 1075, and the ratio to this dihydrochloride is 1.075.