首页> 外国专利> 2-AMINO-4-PHENYL-4-OXO-BUTTERIC ACID DERIVATIVES WITH KYNURENINASE AND / OR KYNURENIN-3-HYDROXYLASE INHIBITING EFFECT

2-AMINO-4-PHENYL-4-OXO-BUTTERIC ACID DERIVATIVES WITH KYNURENINASE AND / OR KYNURENIN-3-HYDROXYLASE INHIBITING EFFECT

机译:具有KY激酶和/或KY抑制剂的2-氨基氨基-4-苯基-4-氧代酸衍生物

摘要

Use in the prevention and/or in the treatment of neurodegenerative diseases of 2-amino-4-phenyl-4-oxo-butyric acid derivatives which act as kynureninase enzyme inhibitors and/or kynurenine-3-hydroxylase enzyme inhibitors. Several of these derivatives are new and, as such, constitute a further object of this invention, together with the process for their preparation and the pharmaceutical compositions containing them.
机译:用于预防和/或治疗神经退行性疾病的2-氨基-4-苯基-4-氧代丁酸衍生物,它们用作犬尿氨酸酶抑制剂和/或犬尿氨酸-3-羟化酶抑制剂。这些衍生物中的几种是新的,并因此构成本发明的另一个目的,以及它们的制备方法和含有它们的药物组合物。

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