USE OF IDEBENONE AND ANALOGUES AGAINST BETA AMYLOID INDUCED CYTOTOXICITY

摘要

A compound of formula (I) or (II) wherein R1 represents a lower alkyl; R2represents H, an optionally substituted alkyl or an optionally substitutedalkenyl; R3 and R4 each represents an optionally substituted lower alkyl or alower alkoxy, or R3 and R4 form, taken together, an optionally substitutedbutadienylene; and X1 and X2 each represents an optionally esterified oretherified hydroxy, or a salt thereof is useful for protecting cells from thecytotoxicity of .beta.-amyloid protein.