USE OF IDEBENONE AND ANALOGUES AGAINST BETA AMYLOID INDUCED CYTOTOXICITY

摘要

A compound of formula (I) or (II) wherein R1 represents a lower alkyl; R2 represents H, an optionally substituted alkyl or an optionally substituted alkenyl; R?3 and R4¿ each represents an optionally substituted lower alkyl or a lower alkoxy, or R?3 and R4¿ form, taken together, an optionally substituted butadienylene; and X?1 and X2¿ each represents an optionally esterified or etherified hydroxy, or a salt thereof is useful for protecting cells from the cytotoxicity of β-amyloid protein.