New retinoic acid esters of antibiotics, process for their preparation and pharmaceutical and cosmetic compositions containing them

摘要

A compound which is an all-trans- or 13-cis-retinoic acid ester of erythromycin A, lincomycin or clindamycin, or a salt thereof, or a mixture of such compounds is useful in the treatment of various dermatitides, especially acne. The compound may have the formula:- IMAGE