HEMOGLOBIN REAGENT COMPOSITION CONTAINING CYANIDE AND METHOD FOR PROVIDING PERMISSIBLE PRECISION AND ACCURACY BY AUTOMATIC BLOOD ANALYZER AND FREE OF INTERFERENCE DUE TO LEUCOCYTE

摘要

PROBLEM TO BE SOLVED: To provide a stable reagent composition and method improved for measuring hemoglobin (Hb) employing all blood specimen and automatic liquid analyzer, for example, a device of TECHNICON HTM series to be sold by an assignee. SOLUTION: A Hb reagent composition containing salt of an inorganic cyanide, at least one kind of critical activator and chloride and having final pH of about 10.0 to about 11.2, preferably less than about 10.4 to about 11.2, and more preferably less than about 10.8 to about 11.2, and a method for measuring hemoglobin in a blood specimen using this composition. This reagent is suitable to use as a general-purpose Hb measuring reagent for all devices of the above series, and brings accurate and precise results without interference found out in an abnormal blood specimen in particular caused by leucocyte with its increased number and without intra-system variation in the result obtained.