Autonomously replicable recombinant DNA in cells of bacteria corineformes, bacteria corineforme harboring a aspartoquinase, process to produce L - Lisa, DNA, vector and pvk7

摘要

"Autonomously replicable recombinant DNA in cells of bacteria corineformes, bacteria corineforme harboring a aspartoquinase, process to produce L - Lisa, DNA, and vector pvk7".A bacterium corineforme harboring a aspartoquinase in which feedback inhibition by L-lysine and L - threonine is substantially dessensibilizada,And comprising a DNA sequence encoding for improved reductase di - hidrodipicolinato, a DNA sequence coding for di - hidropicolinato improved reductase.A DNA sequence coding for improved synthase di - hidropicolinato, a DNA sequence coding for diaminopimelato improved decarboxylase.And a sequence DNA improved coding for aminotransferase aspartate.A process for producing L-lysine comprising the steps of cultivating the bacterium in a suitable medium for corineforme allow L-lysine is produced and accumulated in a culture of bacteria.And collect L-lysine from the culture; and a recombinant DNA usable for production of bacterium corineforme.