SUBSTITUTED N-METHYL-N-(4-(4-(1H-BENZIMIDAZOL-2-YL-AMINO)PIPERIDIN-1-YL)-2-(ARYL)BUTYL)BENZAMID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND USE THEREOF

摘要

In the general formula (I) of the title compounds, R 'is hydrogen, halogen, -OCF3, alkyl or alkoxy, R' is optionally substituted triazolyl or tetrazolyl, Ar1 is optionally pyridyl, naphthyl, ar1 is optionally substituted - or thienyl thistle, X is (g) or (h) a thymyl of general formula wherein R3 is hydrogen, halogen, -CF3, alkyl or alkoxy, and R4 is selected from the group consisting of allergic rhinitis, asthma, emesis and inflammatory bowel diseases. ŕ