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4-AMINOETHOXY-INDOLONE DERIVATIVES AS DOPAMINE D2 AGONISTS

机译:4-氨基乙氧基吲哚酮衍生物作为多巴胺D2激动剂

摘要

A compound of formula (I) in which Y is hydrogen, halogen or alkoxy; R is hydrogen or alkylthio; R1 is hydrogen or alkyl; X is hydrogen, halogen, alkoxy, alkyl or phenyl; n is one of the integers 1, 2, 3 or 4; or a pharmaceutically acceptable salt thereof are inhibitors of dopamine synthesis and release, useful in the treatment of shizophrenia, Parkinson's Disease, Tourette's Syndrome, alcohol addiction, cocaine addiction, and addiction to analogous drugs.
机译:式(I)的化合物,其中Y是氢,卤素或烷氧基; R为氢或烷硫基; R1是氢或烷基; X是氢,卤素,烷氧基,烷基或苯基; n是1、2、3或4的整数之一;或其药学上可接受的盐是多巴胺合成和释放的抑制剂,可用于治疗精神分裂症,帕金森氏病,图雷特氏综合症,酒精成瘾,可卡因成瘾以及对类似药物的成瘾。

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