method of determination of u0431u043bu0430u0441u0442u043eu043cu043eu0433u0435u043du043du043eu0439 activity of chemicals by baiting animals research substance and the slaughtering of animals and the definition of ism u0435u043du0435u043du0438u044f activity of enzymes in the liver, and the fact that, in order to simplify the way through reduction of baiting animals explored chemical lead the threshold dose, acute actions within a week of dailydetermine the activity u043au0430u0442u0430u043bu0430u0437u044b, glutathione peroxidase, the content of u0433u043bu0443u0442u0430u0442u0438u043eu043du0430 and u043au043eu043du044au044eu0433u0438u0440u043eu0432u0430u043du043du044bu0445 u0434u0438u0435u043du043eu0432 in liver, and while reducing the ak u043au0430u0442u0430u043bu0430u0437u044b and glutathione peroxidase of more than 50% compared with the control.u0433u043bu0443u0442u0430u0442u0438u043eu043du0430 increase of more than 50% and u043au043eu043du044au044eu0433u0438u0440u043eu0432u0430u043du043du044bu0445 u0434u0438u0435u043du043eu0432 more than 100% are u0431u043bu0430u0441u0442u043eu043cu043eu0433u0435u043du043du0443u044e active chemical in u0445u0440u043eu043du0438u0447u0435u0441u043a oh intoxication.
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