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Imidazo (1,2-a) pyridines as bradykinin antagonists

机译:咪唑(1,2-a)吡啶作为缓激肽拮抗剂

摘要

A compound of the formula : CHEM wherein R1 is halogen, R2 and R3 are each hydrogen, lower alkyl, halo(lower)alkyl or acyl, R4 is aryl having suitable substituent(s), or a heterocyclic group optionally having suitable substituent(s), Q is O or N-R11, in which R11 is hydrogen or acyl, and A is lower alkylene, and pharmaceutically acceptable salts thereof, processes for their preparation and pharmaceutical compositions comprising them as an active ingredient.
机译:式:的化合物,其中R 1为卤素,R 2和R 3各自为氢,低级烷基,卤代(低级)烷基或酰基,R 4为具有合适取代基的芳基药学上可接受的一个或多个杂环基,或任选具有合适取代基的杂环基,Q为O或NR 1 1,其中R 1 1为氢或酰基,A为低级亚烷基,其可接受的盐,其制备方法和包含它们作为活性成分的药物组合物。

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